Studying kinetics of release medicinal substances from chitosan films

Doklady Bashkirskogo Universiteta. 2021. Volume 6. No. 1. pp. 8-13.

Authors


Shurshina A. S.
Bashkir State University
32 Zaki Validi Street, 450076 Ufa, Republic of Bashkortostan, Russia
Lazdina M. Yu.*
Bashkir State University
32 Zaki Validi Street, 450076 Ufa, Republic of Bashkortostan, Russia

Abstract


The kinetics of controlled release of medicinal substances from chitosan films has been investigated. Correlation between values of coefficients diffusion and shares of medicinal substance connected with a polymeric chain has been established. It was shown that the greater proportion of the medicinal substance connected with a polymeric chain, the lower the value of diffusion coefficients and the index defining process of diffusion in the chitosan films, and the slower transport of medicinal substance from a polymeric matrix.

Keywords


  • хитозан
  • лекарственное вещество
  • диффузия
  • аномальный характер